Modality.AI

Webinar recording:ALS Caregiving, Technology, and Trial Inclusion

Self-Guided Clinical Assessments

Science-First. Objective. Reliable.

Modality.AI redefines how neurological and psychiatric conditions are assessed in clinical research. We’ve built a reliable, science-first, multimodal assessment platform that turns structured conversations into precise measures of speech, facial expression, and motor function—without requiring a clinic visit, dedicated device, or clinical rater.

Designed for Rigorous Clinical Trials

The Modality Platform is built to meet the demands of regulated trials, supporting both in-clinic and remote administration. Sponsors use Modality to supplement (and in some instances, replace) rater-based assessments with automated measures that reduce subjectivity and increase statistical power. By combining speech, facial, and motor-movement analytics in a single session, Modality generates results in minutes. Data is processed by Modality's secure and HIPAA-compliant AI platform in real-time. Results are explainable and auditable.

Tina works with internet-connected computers, tablets and phones.

Say “Hello” to Tina

The Modality Platform utilizes real-time audiovisual dialog with virtual guide "Tina" to standardize assessment across sites and languages, reduce site burden, and enable effective decentralized trials. Designed by scientists and validated in clinical studies, Tina transforms structured conversations into rich, objective clinical data—helping sponsors detect subtle changes, reduce trial noise, and accelerate time to insight.

Science-Driven, Clinically Validated

Modality’s protocols are grounded in decades of peer-reviewed research across ALS, Parkinson’s disease, schizophrenia, depression, autism, and more. Our digital measures are designed to align with clinical endpoints and demonstrate sensitivity to disease progression and treatment response.

Real-World Use in Global Trials

Pharma and biotech sponsors, including top-10 biopharma, trust Modality to support studies, whether natural history studies or FDA-regulated clinical trials. Protocols are available in more than a dozen languages and dialects, and data may be stored in select regions to support privacy standards such as GDPR.

Representative examples, see our Partners page for a more comprehensive list.

Guided by Experience, Built by Experts

Behind the Modality Platform is a team with extensive experience in developing enterprise-scale AI systems. We collaborate closely with our clinical advisors, sponsors, and sites to ensure that every study is designed and implemented for success.

Let’s Talk

Whether you’re planning an early-stage observational study or a high-stakes clinical trial, we would be happy to discuss how Modality can support your goals.